RNA editing: a driving force for adaptive evolution?
نویسندگان
چکیده
منابع مشابه
RNA editing and the evolution of parasites.
The kmeloplaslid flagellates, together \Villi lllcil SlSl¢l ~lOUp (d euglenoid>, represenl ]lie, earlies| extan* }incage of eukaryotIc c~rgani>ms conlainnlg milocbondria (]). \Xzilbu: file kinen~plaslids, there arc two maj<~l groups, ll~e p,~olly studied bodonidscrypn-4qids, which con>is, of both ttce-lix m~ and parasllit cells, and :be bcuel kilo\vii irypallc~>onlalids, w]licll are i4~hFalc pa...
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Two different RNA editing systems have been described in the kinetoplast-mitochondrion of trypanosomatid protists. The first involves the precise insertion and deletion of U residues mostly within the coding regions of maxicircle-encoded mRNAs to produce open reading frames. This editing is mediated by short overlapping complementary guide RNAs encoded in both the maxicircle and the minicircle ...
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Mitochondrial transcript maturation in African trypanosomes requires a U-nucleotide specific RNA editing reaction. In its most extreme form hundreds of U's are inserted into and deleted from primary transcripts to generate functional mRNAs. Unfortunately, both origin and biological role of the process have remained enigmatic. Here we report a so far unrecognized structural feature of pre-edited...
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ژورنال
عنوان ژورنال: BioEssays
سال: 2009
ISSN: 0265-9247
DOI: 10.1002/bies.200900045